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While the precise mechanism behind this effect is not fully understood, several physiological pathways have been proposed based on clinical observations and pharmacological understanding of GLP-1 receptor agonists

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Key considerations include: Possible GI effects: Exposure could potentially affect appetite or cause mild gastrointestinal symptoms, like diarrhea, though this has not been confirmed in large clinical trials

As one of the most widely prescribed weight-loss medications globally, phentermine has helped countless individuals reduce cardiovascular risk, improve metabolic health, and achieve weight outcomes that diet and exercise alone had not produced

Burnett said his larger concern is not Trump's choice of words but the limited insurance coverage many patients face